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正式的质量改进课程和 DMAIC 方法促成了肾移植患者的跨学科合作和流程改进。

Formal quality improvement curriculum and DMAIC method results in interdisciplinary collaboration and process improvement in renal transplant patients.

机构信息

Mayo Clinic Florida, Department of Transplantation, Division of Transplant Surgery, Jacksonville, Florida 32224, USA.

出版信息

J Surg Res. 2012 Sep;177(1):7-13. doi: 10.1016/j.jss.2012.03.017. Epub 2012 Mar 30.

Abstract

BACKGROUND

Broad-based formal quality improvement curriculum emphasizing Six Sigma and the DMAIC approach developed by our institution is required for physicians in training. DMAIC methods evaluated the common outcome of postoperative hyponatremia, thus resulting in collaboration to prevent hyponatremia in the renal transplant population.

METHODS

To define postoperative hyponatremia in renal transplant recipients, a project charter outlined project aims. To measure postoperative hyponatremia, serum sodium at admission and immediately postoperative were recorded by retrospective review of renal transplant recipient charts from June 29, 2010 to December 31, 2011. An Ishikawa diagram was generated to analyze potential causative factors. Interdisciplinary collaboration and hospital policy assessment determined necessary improvements to prevent hyponatremia. Continuous monitoring in control phase was performed by establishing the goal of <10% of transplant recipients with abnormal serum sodium annually through quarterly reduction of hyponatremia by 30% to reach this goal.

RESULTS

Of 54 transplant recipients, postoperative hyponatremia occurred in 92.6% of patients. These potential causes were evaluated: 1) Hemodialysis was more common than peritoneal dialysis. 2) Alemtuzumab induction was more common than antithymocyte globulin. 3) A primary diagnosis of diabetes existed in 16 patients (30%). 4) Strikingly, 51 patients received 0.45% sodium chloride intraoperatively, suggesting this as the most likely cause of postoperative hyponatremia. A hospital policy change to administer 0.9% sodium chloride during renal transplantation resulted in normal serum sodium levels postoperatively in 59 of 64 patients (92.2%).

CONCLUSION

The DMAIC approach and formal quality curriculum for trainees addresses core competencies by providing a framework for problem solving, interdisciplinary collaboration, and process improvement.

摘要

背景

我们机构开发的、以六西格玛和 DMAIC 方法为基础的广泛的基础规范化质量改进课程,是对受训医师的要求。DMAIC 方法评估了术后低钠血症的常见结果,因此促成了在肾移植人群中预防低钠血症的合作。

方法

为了明确肾移植受者术后低钠血症的定义,项目章程概述了项目目标。通过回顾性审查 2010 年 6 月 29 日至 2011 年 12 月 31 日的肾移植受者病历,记录入院时和术后即刻的血清钠值,以测量术后低钠血症。生成石川图来分析潜在的致病因素。通过跨学科合作和医院政策评估,确定了预防低钠血症所需的改进措施。通过设定每年通过每季度降低 30%使低钠血症减少 30%,从而将异常血清钠的移植受者比例控制在 10%以下的目标,在控制阶段进行持续监测。

结果

在 54 例移植受者中,92.6%的患者出现术后低钠血症。评估了这些潜在原因:1)血液透析比腹膜透析更常见。2)阿仑单抗诱导比抗胸腺细胞球蛋白更常见。3)16 例患者(30%)存在原发性糖尿病诊断。4)令人惊讶的是,51 例患者在术中接受了 0.45%氯化钠,这表明这是术后低钠血症最可能的原因。一项针对医院政策的改变,即肾移植期间给予 0.9%氯化钠,导致 64 例患者中的 59 例(92.2%)术后血清钠水平正常。

结论

受训医师的 DMAIC 方法和规范化质量课程通过提供解决问题、跨学科合作和流程改进的框架,解决了核心能力。

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