Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey.
Taiwan J Obstet Gynecol. 2012 Mar;51(1):89-92. doi: 10.1016/j.tjog.2012.01.018.
Postirradiation sarcoma of the female genital tract is rare, but a recognized event. Most reported cases have been associated with history of radiotherapy for various gynecologic conditions, particularly cancer of the uterine cervix and abnormal uterine bleeding. The occurrence of uterine sarcoma secondary to radiotherapy for a non-gynecologic tumor and, furthermore, this condition being simultaneous with the recurrence of primary tumor is unique.
A 67-year-old woman presented with a uterine mass which was diagnosed as a sarcoma by endometrial curettage and history of pelvic radiotherapy 23 years previously for sacral chordoma. Surgical staging procedure for uterine malignancy was performed. The final pathologic diagnosis was carcinosarcoma of the uterus.
In uterine masses seen in patients with history of irradiation to the pelvic field, the probability of uterine sarcomas should always be kept in mind. These tumors may occur simultaneously with recurrence of primary tumor previously treated by adjuvant radiation therapy.
女性生殖道放射后肉瘤罕见，但确有发生。大多数报道的病例均与各种妇科疾病的放射治疗史相关，尤其是宫颈癌和异常子宫出血。因非妇科肿瘤接受放疗后发生子宫肉瘤，且这种情况与原发性肿瘤复发同时存在，实属罕见。
一位 67 岁女性因盆腔放疗 23 年前为骶骨脊索瘤后出现子宫肿块就诊。行子宫恶性肿瘤的手术分期。最终病理诊断为子宫癌肉瘤。
在盆腔照射病史的患者中出现子宫肿块时，应始终考虑到发生子宫肉瘤的可能性。这些肿瘤可能与先前接受辅助放疗的原发性肿瘤复发同时发生。
