Neurology Department, Hospital de Pediatría Prof. Dr. Juan P Garrahan, Buenos Aires, Argentina.
Epilepsy Res. 2012 Aug;101(1-2):185-90. doi: 10.1016/j.eplepsyres.2012.03.008. Epub 2012 Apr 5.
In this study, we describe three patients who each had an electroclinical overlap of two different epileptic encephalopathies (EE), with onset in a certain age period. Patient 1 had electroclinical features compatible with continuous spikes and waves during slow sleep (CSWSS) syndrome that changed into Lennox-Gastaut syndrome (LGS) (symptomatic, cause porencephalic cyst) at the age of 8.5 years. Patient 2 had LGS which evolved into CSWSS at the age of 6 years (symptomatic, cause polymicrogyria). The third patient had cryptogenic CSWSS syndrome at age the age of 7 years which evolved into LGS at the age of 7.5 years. All three patients could be considered to have two EE: CSWSS syndrome and LGS or to have had overlapping features of these epileptic syndromes.
在这项研究中，我们描述了 3 名患者，他们每人都有两种不同的癫痫性脑病（EE）的电临床重叠，发病于特定年龄段。患者 1 具有与睡眠中持续棘慢波（CSWSS）综合征一致的电临床特征，在 8.5 岁时转变为 Lennox-Gastaut 综合征（LGS）（症状性，原因是脑裂畸形）。患者 2 患有 LGS，在 6 岁时发展为 CSWSS（症状性，原因是多小脑回畸形）。第三位患者在 7 岁时患有隐源性 CSWSS 综合征，在 7.5 岁时发展为 LGS。这 3 名患者都可以被认为患有两种 EE：CSWSS 综合征和 LGS，或者具有这些癫痫综合征的重叠特征。
