Department of Physical Therapy, University of Illinois at Chicago, IL 60612, USA.
Gait Posture. 2012 Jun;36(2):225-30. doi: 10.1016/j.gaitpost.2012.02.022. Epub 2012 Apr 5.
The aim of the present study was to investigate the organization of anticipatory postural adjustments (APAs) in individuals with multiple sclerosis (MS) during self-initiated perturbation in the sagittal plane. Eleven individuals with MS and eleven age-and-gender matched healthy controls were asked to hold a 2.27 kg load in the extended arms and release it using fast arm abduction movements. Electrical activity of six leg and trunk muscles as well as displacements of the center of pressure (COP) were recorded. The results indicate that individuals with MS (1) demonstrate a reduced magnitude of APAs, (2) delayed latency of APAs and (3) smaller anticipatory COP displacement as compared to healthy control subjects. Moreover, in spite of individuals with MS being mildly affected, their balance capacity was significantly diminished. Thus, the outcome of this study demonstrates the underlying impairment in anticipatory postural control of individuals with MS and provides a background for development of rehabilitation strategies focused on balance restoration in this population.
本研究旨在探讨多发性硬化症（MS）患者在矢状面自主产生扰动时的预期姿势调整（APAs）的组织情况。11 名 MS 患者和 11 名年龄和性别匹配的健康对照者被要求将 2.27 公斤的负荷举在伸展的手臂上，并通过快速手臂外展运动将其释放。记录了 6 条腿部和躯干肌肉的电活动以及中心压力（COP）的位移。结果表明，与健康对照组相比，MS 患者（1）APAs 的幅度较小，（2）APAs 的潜伏期延迟，（3）预期 COP 位移较小。此外，尽管 MS 患者受影响程度较轻，但他们的平衡能力明显下降。因此，这项研究的结果表明，MS 患者的预期姿势控制存在潜在障碍，并为针对该人群平衡恢复的康复策略的发展提供了背景。
