Shozawa T
Second Department of Pathology, Akita University School of Medicine, Japan.
Ann N Y Acad Sci. 1990;598:435-43. doi: 10.1111/j.1749-6632.1990.tb42314.x.
Of sixty-four acute myocardial infarcts showing myocardial necrosis within 5 days after onset, 37 had fresh coronary occlusive thrombi with recent thrombus in the deep layer. The recent thrombi were usually located in the severely stenosed segment of arteriosclerotic coronary arteries. They adhered to the intima not only near but on the opposite site to the plaque ulcers and sometimes covered the ulcer. In two thirds of the cases, both the recent thrombi and plaque ulcers were located in the same segment. In the others, the topographical relationship of plaque ulcers to recent thrombi in the longitudinal direction varied from one case to another. These findings show that the recent thrombus might play an important role in the formation of a fresh occlusive thrombus and plaque ulcer of coronary arteriosclerotic lesions.
在64例发病后5天内出现心肌坏死的急性心肌梗死患者中，37例有新鲜的冠状动脉闭塞性血栓，且深层有近期血栓形成。近期血栓通常位于动脉粥样硬化冠状动脉的严重狭窄段。它们不仅附着在斑块溃疡附近的内膜上，而且附着在斑块溃疡相对侧的内膜上，有时还覆盖溃疡。在三分之二的病例中，近期血栓和斑块溃疡位于同一节段。在其他病例中，斑块溃疡与近期血栓在纵向上的位置关系因病例而异。这些发现表明，近期血栓可能在冠状动脉粥样硬化病变的新鲜闭塞性血栓和斑块溃疡形成中起重要作用。
