Porubčin Štefan, Porubčinová I, Kristian P, Virág L, Štammová E, Vyhnánková V, Paraličová Z
Klinika infektológie a cestovnej medicíny, UNLP a LF UPJŠ, Košice.
Klin Mikrobiol Infekc Lek. 2012 Feb;18(1):17-21.
We present a rare case of combined fungal infection in a critically ill 47 year-old patient with chronic hepatitis C at the stage of liver cirrhosis. The patient was admitted for signs of decompensated cirrhosis caused by hepatitis C and increased alcohol consumption. After 2 week hospital stay, his condition was complicated by a pulmonary infiltrate and rapid deterioration followed. Despite intensive care, the patient died. Autopsy findings showed invasive pulmonary aspergillosis. The aim of this case report is to point to a broad differential diagnosis of jaundice and pulmonary infiltrates, thus stressing the value of interdisciplinary cooperation and the need to consider the possibility of invasive fungal infections when caring for liver cirrhosis patients. In addition, several risk factors contributing to the development of fungal diseases in these patients are discussed in the article.
我们报告了一例罕见的合并真菌感染病例，患者为一名47岁的重症患者，患有处于肝硬化阶段的慢性丙型肝炎。该患者因丙型肝炎导致的肝硬化失代偿体征及饮酒量增加而入院。住院2周后，他的病情因肺部浸润而复杂化，随后迅速恶化。尽管进行了重症监护，患者仍死亡。尸检结果显示为侵袭性肺曲霉病。本病例报告的目的是指出黄疸和肺部浸润的广泛鉴别诊断，从而强调跨学科合作的价值以及在护理肝硬化患者时考虑侵袭性真菌感染可能性的必要性。此外，本文还讨论了导致这些患者发生真菌疾病的几个危险因素。
