Collins J E, Leonard J V, Teale D, Marks V, Williams D M, Kennedy C R, Hall M A
Department of Child Health, Institute of Child Health, London.
Arch Dis Child. 1990 Oct;65(10):1118-20. doi: 10.1136/adc.65.10.1118.
Blood glucose concentrations were measured prospectively in 27 small for dates infants in the first 48 hours after birth: 10 infants became hypoglycaemic. Of these, five had inappropriately raised plasma insulin concentrations. Plasma free fatty acids were lower and carbohydrate intake higher in these five infants, further supporting the diagnosis of hyperinsulinism. The hypoglycaemia recurred in four of the five hyperinsulinaemic infants, but in none of those who were not hyperinsulinaemic. Hyperinsulinism is common in small for dates babies. It is important to recognise this because hypoglycaemia is likely to recur and appropriate treatment is needed to prevent long term sequelae.
对27名小于胎龄儿在出生后的头48小时内进行了前瞻性血糖浓度测量：10名婴儿出现低血糖。其中，5名婴儿的血浆胰岛素浓度异常升高。这5名婴儿的血浆游离脂肪酸较低，碳水化合物摄入量较高，进一步支持了高胰岛素血症的诊断。5名高胰岛素血症婴儿中有4名再次出现低血糖，但非高胰岛素血症婴儿中无人出现低血糖。高胰岛素血症在小于胎龄儿中很常见。认识到这一点很重要，因为低血糖可能会复发，需要进行适当治疗以防止长期后遗症。
