University Psychiatric Centre Katholieke Universiteit Leuven, Campus Kortenberg, Belgium.
Acta Psychiatr Scand. 2012 Jul;126(1):12-20. doi: 10.1111/j.1600-0447.2012.01865.x. Epub 2012 Apr 6.
The objective of this systematic review was to assess the effectiveness of yoga as a complementary treatment on general psychopathology, positive and negative symptoms and health-related quality of life (HRQL) for people with schizophrenia.
Randomised controlled trials (RCTs) were considered whether they investigated a yoga intervention in patients with schizophrenia. The selection of studies, data extraction and quality assessment were performed independently by two reviewers.
Only three RCTs met the inclusion criteria. Lower Positive and Negative Syndrome Scale (PANSS) total scores and subscale scores for positive and negative symptoms were obtained after yoga compared with exercise or waiting list control conditions. In the same way, the physical, psychological, social and environmental HRQL as measured with the abbreviated version of the World Health Organization Quality of Life questionnaire (WHOQOL-BREF) increased more significantly after yoga than after exercise or waiting list control conditions. None of the RCTS encountered adverse events. Dose-response relationships could, however, not be determined.
Although the number of RCTs included in this review was limited, results indicated that yoga therapy can be an useful add-on treatment to reduce general psychopathology and positive and negative symptoms. In the same way, HRQL improved in those antipsychotic-stabilised patients with schizophrenia following yoga.
本系统评价旨在评估瑜伽作为一种补充治疗对精神分裂症患者的一般精神病理学、阳性和阴性症状以及与健康相关的生活质量（HRQL）的有效性。
考虑了随机对照试验（RCT），无论它们是否在精神分裂症患者中调查了瑜伽干预。两名评审员独立进行了研究选择、数据提取和质量评估。
仅符合纳入标准的三项 RCT。与运动或等待名单对照条件相比，瑜伽后阳性和阴性综合征量表（PANSS）的总分和阳性及阴性症状的子量表评分较低。同样，使用世界卫生组织生活质量问卷（WHOQOL-BREF）的简化版衡量的身体、心理、社会和环境 HRQL 在瑜伽后比运动或等待名单对照条件后增加得更为显著。但是，没有 RCT 遇到不良反应。然而，无法确定剂量反应关系。
尽管本综述纳入的 RCT 数量有限，但结果表明瑜伽疗法可以作为一种有用的附加治疗方法，以减少一般精神病理学和阳性及阴性症状。同样，在接受抗精神病药物稳定治疗的精神分裂症患者中，瑜伽后 HRQL 也得到了改善。
