甲状旁腺疾病患者的血液镁状态。
Blood magnesium status of patients with parathyroid disease.
作者信息
Elin R J, Hosseini J M, Fitzpatrick L, Bliziotes M M, Marx S J
机构信息
Clinical Pathology Department, National Institute of Diabetes, and Digestive and Kidney Diseases, Bethesda, Md.
出版信息
Magnes Trace Elem. 1990;9(3):119-23.
The blood magnesium status--plasma and red blood cell (RBC) concentration and mononuclear blood cell (MBC) content of magnesium and parathyroid hormone (PTH) were determined in 6 patients with chronic hypoparathyroidism and 9 patients with primary hyperparathyroidism before and after surgical cure of the disease. The magnesium content of MBCs and concentration of RBCs increased significantly (p less than 0.01) after the surgical correction of primary hyperparathyroidism. Patients with chronic hypoparathyroidism had significant increase (p less than 0.05) of magnesium in RBCs and MBCs compared with the control group. No significant difference was observed for the plasma magnesium concentration for hypoparathyroid patients compared with the control group and hyperparathyroid patients before and after surgical care. These results suggest that endogenous PTH affects the concentration of magnesium in RBCs and magnesium content in MBCs but does not alter significantly the concentration of magnesium in plasma.
测定了6例慢性甲状旁腺功能减退患者和9例原发性甲状旁腺功能亢进患者在疾病手术治愈前后的血液镁状态——血浆和红细胞（RBC）中镁的浓度以及单核血细胞（MBC）中镁和甲状旁腺激素（PTH）的含量。原发性甲状旁腺功能亢进手术矫正后，MBC中的镁含量和RBC中的浓度显著增加（p<0.01）。与对照组相比，慢性甲状旁腺功能减退患者的RBC和MBC中的镁显著增加（p<0.05）。与对照组以及甲状旁腺功能亢进患者手术治疗前后相比，甲状旁腺功能减退患者的血浆镁浓度未观察到显著差异。这些结果表明，内源性PTH影响RBC中镁的浓度和MBC中镁的含量，但不会显著改变血浆中镁的浓度。
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