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肾肿瘤消融术能否提供充分的长期肿瘤控制效果?

Does renal mass ablation provide adequate long-term oncologic control?

机构信息

Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, J8.106, Dallas, TX 75390, USA.

出版信息

Urol Clin North Am. 2012 May;39(2):181-90, vi. doi: 10.1016/j.ucl.2012.01.004. Epub 2012 Feb 16.

Abstract

Renal ablation (RA) is no longer used exclusively in patients with limited life expectancy. There are few studies reporting a minimum follow-up of 5 years. Biases and discrepancies within the literature are abundant. The outcomes of any series must be interpreted in the context of median follow-up time, reported tumor characteristics, ablation technique and training background of the practitioner, and the definition of tumor recurrence. The long-term oncologic efficacy of radiofrequency ablation (RFA) and cryoablation appear similar, although the percutaneous RFA technique may necessitate reablation in more cases. RA is associated with slightly higher rates of local recurrence compared to surgical excision.

摘要

肾切除术(RA)不再仅用于预期寿命有限的患者。很少有研究报告随访时间至少为 5 年。文献中存在大量的偏见和差异。任何系列的结果都必须结合中位随访时间、报告的肿瘤特征、消融技术和医生的培训背景以及肿瘤复发的定义来解释。射频消融(RFA)和冷冻消融的长期肿瘤学疗效似乎相似,尽管经皮 RFA 技术可能需要在更多情况下进行再消融。与手术切除相比,RA 局部复发率略高。

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