Squires Nina, Wills Adrian, Rowson John
Speech and Language Therapy Department, Queen's Medical Centre, Nottingham, UK.
Curr Opin Otolaryngol Head Neck Surg. 2012 Jun;20(3):171-6. doi: 10.1097/MOO.0b013e32835328ec.
Drooling is a distressing symptom for adults with neurological conditions and can be challenging for health professionals. This review will consider the physical and psychosocial impact of drooling and will discuss the current management options including behavioural, pharmacological and surgical approaches.
A number of studies describe the use of botulinum toxin injections and irradiation of the salivary glands but no conclusive guidelines exist to recommend the most efficient dose or technique. The majority of saliva management studies focus on children with physical and/or cognitive disabilities and this evidence cannot be generalized to adults. There are relatively few studies that focus on saliva management in the adult neurological population.
Drooling is distressing for patients and their families. Ideally an individual would have easy access to the most efficient treatment with the fewest side effects. More evidence is now available but a lack of consensus on management approach, treatment dose and administration technique still exists. The symptom of drooling is best managed by a multidisciplinary team, starting with a conservative approach and then leading to more invasive procedures as appropriate.
流涎对于患有神经系统疾病的成年人来说是一种令人苦恼的症状,对医疗专业人员而言也颇具挑战性。本综述将探讨流涎对身体和心理社会的影响,并讨论当前的管理方案,包括行为、药物和手术方法。
多项研究描述了肉毒杆菌毒素注射和唾液腺照射的应用,但尚无确凿指南来推荐最有效的剂量或技术。大多数唾液管理研究聚焦于有身体和/或认知障碍的儿童,而这些证据不能推广至成年人。相对较少的研究关注成年神经疾病患者的唾液管理。
流涎令患者及其家人苦恼。理想情况下,个人应能轻松获得副作用最少的最有效治疗。现有更多证据,但在管理方法、治疗剂量和给药技术方面仍缺乏共识。流涎症状最好由多学科团队管理,首先采用保守方法,然后根据情况采用更具侵入性的程序。