Department of Anesthesiology and Perioperative Care, University of California, Irvine, Orange, California 92868, USA.
Curr Opin Anaesthesiol. 2012 Jun;25(3):321-5. doi: 10.1097/ACO.0b013e3283530e0d.
Preparation for and induction of anesthesia in children has evolved significantly over the last decade, with particular reference to the reduction of perioperative anxiety reduction by nonpharmacologic and pharmacologic means. Several new large population studies and meta-analyses further scrutinize the current techniques.
Many nonpharmacologic methods to reduce anxiety are effective λU similar to sedative premedications, with the exception of parent present induction of anesthesia. Healthcare providers can be taught to increase anxiety-reducing behaviors through an educational intervention. Clonidine and dexmedetomidine have many similar or superior qualities to midazolam.
Larger studies still need to be conducted before wide-scale application of many nonpharmalogical interventions such as parental acupuncture. Similarly, more investigation should be done on outcomes such as onset, emergence, and discharge times, as well as the postoperative response with reference to emergence delirium and postoperative nausea and vomiting prevention to outline the differences among sedative premedications such as midazolam, clonidine, and dexmedetomidine.
在过去十年中,儿童麻醉的准备和诱导发生了重大变化,特别关注通过非药物和药物手段减少围手术期焦虑。几项新的大型人群研究和荟萃分析进一步仔细研究了当前的技术。
许多非药物方法可有效减轻焦虑,效果与镇静性预给药相似,但父母陪同诱导麻醉除外。通过教育干预,医疗保健提供者可以被教导增加减轻焦虑的行为。可乐定和右美托咪定具有许多与咪达唑仑相似或更优的特性。
在广泛应用许多非药物干预措施(如父母针刺)之前,还需要进行更大规模的研究。同样,应该对诸如起效、苏醒和出院时间以及术后反应(与苏醒性谵妄和预防术后恶心呕吐相关)等结果进行更多的研究,以阐明咪达唑仑、可乐定和右美托咪定等镇静性预给药之间的差异。