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色素沉着干皮病并发鳞状细胞癌伴眶部蝇蛆病。

Orbital myiasis complicating squamous cell carcinoma in xeroderma pigmentosum.

作者信息

Kamal Saurabh, Bodh Sonam Angmo, Kumar Sushil, Goel Ruchi

机构信息

Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.

出版信息

Orbit. 2012 Apr;31(2):137-9. doi: 10.3109/01676830.2011.638103.

Abstract

Ophthalmomyiasis is a rare infection seen in susceptible individuals. We report a case of orbital myiasis in squamous cell carcinoma (SCC) in a patient of xeroderma pigmentosum. On presentation, reddish brown ulcerated mass with numerous maggots in orbit were seen. Computed tomography scan showed the presence of soft tissue lesion without any bony destruction. Following debridement, emergency exenteration with sacrifice of eyelid skin was performed. The diagnosis of SCC was confirmed on histopathologic evaluation. The maggots belonged to family Calliphoridae and secondary bacterial infection with Klebsiella organism was identified. Management issues included extensive involvement requiring exenteration, non-availability of skin graft, delayed secondary healing and recurrence of pigmented lesions in skin lining of orbit. The skin grafting was avoided as it can harbour the neoplasm.

摘要

眼部蝇蛆病是一种在易感个体中罕见的感染。我们报告了一例着色性干皮病患者鳞状细胞癌(SCC)伴眶部蝇蛆病的病例。就诊时,可见眼眶内有红棕色溃疡肿物,并有大量蛆虫。计算机断层扫描显示存在软组织病变,无任何骨质破坏。清创后,进行了紧急眼眶内容剜除术,牺牲了眼睑皮肤。组织病理学评估确诊为SCC。蛆虫属于丽蝇科,同时鉴定出伴有克雷伯菌属的继发性细菌感染。处理问题包括广泛累及需要进行眼眶内容剜除术、无法获得皮肤移植、二期愈合延迟以及眼眶内衬皮肤色素沉着病变复发。由于皮肤移植可能会隐匿肿瘤,因此未进行皮肤移植。

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