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在埃塞俄比亚西北部贡德尔大学医院接受随访的高血压患者的抗高血压治疗依从性及相关因素。

Adherence to antihypertensive treatment and associated factors among patients on follow up at University of Gondar Hospital, Northwest Ethiopia.

出版信息

BMC Public Health. 2012 Apr 10;12:282. doi: 10.1186/1471-2458-12-282.

Abstract

BACKGROUND

Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital.

METHOD

Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16.

RESULTS

More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence.

CONCLUSION

Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients.

摘要

背景

高血压是一个全球性的重大挑战,其发病率和死亡率都很高。据估计,埃塞俄比亚的高血压患病率为 6%,亚的斯亚贝巴为 30%。不遵医嘱与疾病预后不良和医疗资源浪费有关。在埃塞俄比亚,特别是在研究地区,人们对高血压患者的治疗依从性及其相关因素知之甚少。因此,本研究旨在评估在贡德尔大学教学医院接受随访的高血压患者的降压治疗依从性及其相关因素。

方法

本研究采用基于机构的横断面研究。采用系统抽样技术选取了 384 名参与者。在修改后的情况下使用结构化标准问卷。采用 Morisky 药物依从性量表将患者标记为依从或不依从。使用 SPSS 版本 16 输入和分析数据。

结果

研究参与者中有超过一半(64.6%)被发现对治疗依从。性别(AOR=0.48,95%CI=0.28,0.82)、高血压及其治疗知识(AOR=6.21,95%CI=3.22,11.97)、与医院的距离(AOR=2.02,95%CI=1.19,3.43)和合并症(AOR=2.5,95%CI=1.01,6.21)变量与治疗依从性显著相关。

结论

只有 64.6%的研究对象被发现对治疗依从。性别、与医院的距离、合并症的数量、高血压及其治疗知识等因素与患者的依从行为有关。早期诊断和管理合并症、对患者进行依从性咨询和疾病及其治疗教育,对改善患者的依从性状态非常重要。

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