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单纯疱疹病毒性脑炎后出现的 Charles Bonnet 综合征。

Charles Bonnet syndrome after herpes simplex encephalitis.

机构信息

Department of Pediatric Neurology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.

出版信息

Pediatr Neurol. 2012 Apr;46(4):250-2. doi: 10.1016/j.pediatrneurol.2012.02.010.

DOI:10.1016/j.pediatrneurol.2012.02.010
PMID:22490773
Abstract

Visual impairment associated with Charles Bonnet syndrome is rarely reported in childhood. We describe a child who presented with visual hallucinations and postinfectious bilateral retrobulbar optic neuritis. The patient had undergone acyclovir therapy for 3 weeks because of herpes encephalitis. Four days after therapy was completed, he experienced visual impairment in both eyes. He manifested a bilateral decrease in visual acuity, with normal funduscopic findings. The patient experienced visual hallucinations for about 1 week, and then experienced total loss of vision. During his hallucinations, the patient did not exhibit behavioral changes or cognitive impairment. The visual hallucinations included unfamiliar children hiding under his bed, and he spoke to someone whom he did not know. Magnetic resonance imaging indicated bilateral optic nerve hyperintensity on T(2)-weighted and contrast-enhanced images. The patient received corticosteroid therapy for his retrobulbar optic neuritis, and his vision returned to normal after 1 month. Although rare, visual impairment can be associated with complex visual hallucinations indicative of Charles Bonnet syndrome.

摘要

与 Charles Bonnet 综合征相关的视力障碍在儿童中很少见报道。我们描述了一位因疱疹性脑炎接受阿昔洛韦治疗 3 周后出现视觉幻觉和感染后双侧球后视神经炎的儿童。治疗完成后 4 天,他出现双眼视力障碍。他表现为双侧视力下降,眼底检查正常。患者出现约 1 周的视觉幻觉,随后出现完全失明。在幻觉期间,患者没有表现出行为改变或认知障碍。视觉幻觉包括不熟悉的孩子躲在他的床底下,他和一个不认识的人说话。磁共振成像显示 T2 加权和增强图像上双侧视神经高信号。患者因球后视神经炎接受皮质类固醇治疗,1 个月后视力恢复正常。尽管罕见,但视力障碍可能与表明 Charles Bonnet 综合征的复杂视觉幻觉相关。

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Charles Bonnet syndrome after herpes simplex encephalitis.单纯疱疹病毒性脑炎后出现的 Charles Bonnet 综合征。
Pediatr Neurol. 2012 Apr;46(4):250-2. doi: 10.1016/j.pediatrneurol.2012.02.010.
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[A case of Charles Bonnet syndrome following syphilitic optic neuritis].[一例梅毒相关性视神经炎后发生的邦纳综合征]
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[Complex visual hallucinations in a patient with bilateral visual impairment (Charles Bonnet syndrome)].[一名双侧视力障碍患者的复杂视幻觉(查尔斯·博内综合征)]
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