[冠心病合并慢性肾脏病的患病率及危险因素]

[The prevalence and risk factors of coronary heart disease combined with chronic kidney disease].

作者信息

Sang Xiao-hong, Yan Shu-fang, Sun Yan

机构信息

Department of Nephrology, Xinjiang Medical University, Urumqi, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2012 Feb;51(2):123-6.

PMID:22490813

Abstract

OBJECTIVE

To investigate the prevalence rate and risk factors of inpatients with coronary atherosclerotic heart disease (CHD) combined chronic kidney disease (CKD).

METHODS

All people who underwent CHD combined CKD in CHD department of the First Affiliated Hospital of Xinjiang Medical University during January to December 2009 were enrolled in the retrospective study.

RESULTS

A total of 960 hospitalized patients with CHD were enrolled during the observation period. The prevalence of proteinuria and reduced eGFR were 11.04% and 10.52%, respectively. The total CKD prevalence rate was 16.77%, with male of 16.67% and female of 17.11%. There was no significant difference in prevalence rate between male and female (P > 0.05). The multi-factors logistic regression analysis showed that diabetes mellitus (OR 2.60, 95%CI 1.17 - 3.29) was risk factor for CHD combined proteinuria. Ten-years older in age (OR 1.55, 95%CI 1.31 - 1.83), diabetes mellitus (OR 1.69, 95%CI 1.15 - 2.47), hypercholesterolemia (OR 2.89, 95%CI 1.49 - 5.61), and hyperuricemia (OR 1.49, 95%CI 0.96 - 2.33) were risk factors for CHD combined CKD.

CONCLUSION

More attention should be paid to the high prevalence of CHD combined CKD.

摘要

目的

探讨冠心病（CHD）合并慢性肾脏病（CKD）住院患者的患病率及危险因素。

方法

回顾性研究纳入2009年1月至12月在新疆医科大学第一附属医院冠心病科住院的所有CHD合并CKD患者。

结果

观察期间共纳入960例CHD住院患者。蛋白尿患病率和估算肾小球滤过率（eGFR）降低率分别为11.04%和10.52%。CKD总患病率为16.77%，男性为16.67%，女性为17.11%。男女患病率差异无统计学意义（P>0.05）。多因素logistic回归分析显示，糖尿病（OR 2.60，95%CI 1.17 - 3.29）是CHD合并蛋白尿的危险因素。年龄每增加10岁（OR 1.55，95%CI 1.31 - 1.83）、糖尿病（OR 1.69，95%CI 1.15 - 2.47）、高胆固醇血症（OR 2.89，95%CI 1.49 - 5.61）和高尿酸血症（OR 1.49，95%CI 0.96 - 2.33）是CHD合并CKD的危险因素。