Gu Hong, Liu Ning-pu
Capital Medical University, Beijing, China.
Zhonghua Yan Ke Za Zhi. 2012 Feb;48(2):176-8.
Age related macular degeneration (AMD) is the most common cause of irreversible blindness in the aged population in the western world. AMD is considered to be a multifactorial disease with involvement of both genetic and environmental factors. With the development of molecular biology and molecular genetics, numerous susceptibility genes have been identified. Here we review the recent advances in the genetic studies regarding the AMD susceptibility genes.
年龄相关性黄斑变性（AMD）是西方世界老年人群中不可逆失明的最常见原因。AMD被认为是一种涉及遗传和环境因素的多因素疾病。随着分子生物学和分子遗传学的发展，已经鉴定出许多易感基因。在此，我们综述了关于AMD易感基因的遗传研究的最新进展。
