Li Juan, Hu Yong-hua
Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing, 100191, PR China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2009 Oct;26(5):533-5. doi: 10.3760/cma.j.issn.1003-9406.2009.05.012.
Age-related macular degeneration (AMD) is the leading cause of blindness in industrialized countries. It is a genetically heterogeneous disorder. With the development of molecular biology and molecular genetics, multiple potentially causative genes have been identified. Current studies of susceptibility genes and genetic epidemiology of AMD are reviewed.
年龄相关性黄斑变性(AMD)是工业化国家失明的主要原因。它是一种基因异质性疾病。随着分子生物学和分子遗传学的发展,已鉴定出多个潜在的致病基因。本文综述了目前关于AMD易感基因和遗传流行病学的研究。