Department of Orthopedics, University of Regensburg, Regensburg, Germany.
Int Orthop. 2012 Aug;36(8):1635-40. doi: 10.1007/s00264-012-1530-9. Epub 2012 Apr 11.
In undetached osteochondral lesions (OCL) of the talus both revitalisation of the subchondral necrosis and cartilage preservation are essential. For these cases, we assess the results of minimally invasive retrograde core drilling and cancellous bone grafting.
Forty-one osteochondral lesions of the talus (12x grade I, 22x grade II and 7x grade III according to the Pritsch classification, defect sizes 7-14 mm) in 38 patients (mean age 33.2 years) treated by fluoroscopy-guided retrograde core drilling and autologous cancellous bone grafting were evaluated by clinical scores and MRI. The mean follow-up was 29.0 (±13) months.
The AOFAS score increased significantly from 47.3 (±15.3) to 80.8 (±18.6) points. Lesions with intact cartilage (grades I and II) had a tendency to superior results than grade III lesions (83.1 ± 17.3 vs. 69.4 ± 22.2 points, p = 0.07). First-line treatments and open distal tibial growth plates led to significantly better outcomes (each p < 0.05). Age, gender, BMI, time to follow-up, defect localisation or a traumatic origin did not influence the score results. On a visual analogue scale pain intensity reduced from 7.5 (±1.5) to 3.7 (±2.6) while subjective function increased from 4.6 (±2.0) to 8.2 (±2.3) (each p < 0.001). In MRI follow-ups, five of the 41 patients showed a complete bone remodelling. In two cases demarcation was detectable.
The technique reported is a highly effective therapeutic option in OCL of the talus with intact cartilage grades I and II. However, second-line treatments and grade III lesions with cracked cartilage surface can not be generally recommended for this procedure.
在游离性距骨骨软骨病变(OCL)中,既要使软骨下坏死组织重新活跃,又要保存软骨,这两点都很重要。为此,我们评估了微创逆行钻孔和松质骨移植的效果。
对 38 例患者(平均年龄 33.2 岁)的 41 个距骨骨软骨病变(根据 Pritsch 分类,12 个 I 级、22 个 II 级和 7 个 III 级,缺损大小 7-14mm)进行了透视引导下逆行钻孔和自体松质骨移植治疗,并通过临床评分和 MRI 进行评估。平均随访 29.0(±13)个月。
AOFAS 评分从 47.3(±15.3)显著提高到 80.8(±18.6)分。软骨完整(I 级和 II 级)的病变比 III 级病变有更好的趋势(83.1±17.3 比 69.4±22.2 分,p=0.07)。初次治疗和开放胫骨远端生长板导致显著更好的结果(p<0.05)。年龄、性别、BMI、随访时间、病变定位或创伤来源均未影响评分结果。疼痛强度从 7.5(±1.5)降至 3.7(±2.6),主观功能从 4.6(±2.0)提高到 8.2(±2.3)(均 p<0.001)。在 MRI 随访中,41 例患者中有 5 例出现完全骨重塑。有 2 例出现边界。
对于软骨完整的 I 级和 II 级距骨骨软骨病变,报告的技术是一种非常有效的治疗选择。然而,对于 II 级病变和有裂纹软骨表面的 III 级病变,一般不推荐采用这种方法进行二线治疗。