Berman Brian, Wolf Joel
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Skin Therapy Lett. 2012 Apr;17(4):5-7.
Imiquimod 3.75% cream has recently been approved by both the U.S. Federal Drug Administration and Health Canada for the treatment of external genital warts. Herein, we provide an overview of external genital warts, review the phase 3 clinical trials leading to the approval of imiquimod 3.75% cream, and compare its efficacy and clinical use with imiquimod 5% cream. Moreover, therapeutic options have further expanded with the relatively recent introduction of sinecatechins 15% ointment, an extract of green tea leaves.
咪喹莫特3.75%乳膏最近已获得美国食品药品监督管理局和加拿大卫生部批准，用于治疗外生殖器疣。在此，我们概述外生殖器疣，回顾导致咪喹莫特3.75%乳膏获批的3期临床试验，并将其疗效和临床应用与咪喹莫特5%乳膏进行比较。此外，随着最近相对较新推出的15%儿茶素软膏（一种绿茶提取物），治疗选择进一步扩大。
