Morrish D W, Filipow L J, McEwan A J, Schmidt R, Murland K R, von Westarp C, Betcher K B
Department of Medicine, University of Alberta, Edmonton, Canada.
Cancer. 1990 Dec 15;66(12):2509-13. doi: 10.1002/1097-0142(19901215)66:12<2509::aid-cncr2820661211>3.0.co;2-m.
Procedures for 131I ablation in renal failure are not known. In one patient receiving dialysis, detailed dosimetry and health safety aspects were obtained. The results showed insignificant contamination of equipment, but a surprisingly significant reduction in biologic half-life of 131I due to efficient dialysis extraction. The data indicate that 131I ablation can be done safely and easily during dialysis but that much higher 131I doses must be used to achieve equivalent results to those obtained in patients with normal renal function.
肾衰竭患者进行¹³¹I消融的程序尚不清楚。在一名接受透析的患者中，获取了详细的剂量测定和健康安全方面的信息。结果显示设备污染不显著，但由于高效的透析提取，¹³¹I的生物半衰期出现了惊人的显著缩短。数据表明，¹³¹I消融在透析期间可以安全、轻松地进行，但必须使用高得多的¹³¹I剂量才能达到与肾功能正常患者相同的效果。
