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女性腰椎管狭窄症性腰痛与抑郁的相关性:一项临床研究。

Correlation of low back pain caused by lumbar spinal stenosis and depression in women: a clinical study.

机构信息

Department of Neurosurgery, Selcuk University Selcuklu Medical Faculty, Alaaddin Keykubat Kampüsü, Konya, Turkey.

出版信息

Arch Orthop Trauma Surg. 2012 Jul;132(7):963-7. doi: 10.1007/s00402-012-1513-8. Epub 2012 Apr 12.

DOI:10.1007/s00402-012-1513-8
PMID:22491968
Abstract

OBJECTIVE

Low back pain (LBP) due to spinal stenosis may be one of the most debilitating symptoms to decrease the quality of life. The cause and effect association of LBP and depression is vague. Pain may also be a somatization symptom of depression. This is more frequent in the female population. This clinical study was designed to evaluate the correlation between the level of back pain caused by lumbar spinal stenosis and depression in the female population.

METHOD

The study included 50 consecutive female patients with spinal stenosis. The stenosis diagnosis is made by neurological examination and neuro-imaging. The study group was psychiatrically evaluated and grouped as those with and without depression. Visual analog scale (VAS), Oswestry disability index (ODI) and Hamilton Depression Scale (HDS) were utilized in initial evaluation of the group.

RESULTS

Twenty-one patients with lumbar spinal stenosis had depression (DLS Group) and 29 did not (LSS Group). Mean HDS scores were 8.97 and 32.48 for Group LSS and Group DLS, respectively. There was a statistically significant difference between the VAS scores of the groups (the mean VAS scores were 5.6 and 7.6, for groups LSS and DLS, respectively). The mean ODI values for LSS (65.24 ± 4.58) and DLS (75.1 ± 6.7) groups were also significantly different. In Group DLS, there were positive correlations between ODI and VAS with HDS (p < 0.001).

CONCLUSION

Our findings indicated a relationship between lumbar spinal stenosis associated pain levels and depression. However, the cause and result relationship still needs to be established yet.

摘要

目的

由椎管狭窄引起的下腰痛(LBP)可能是降低生活质量的最具致残性症状之一。LBP 与抑郁之间的因果关系并不明确。疼痛也可能是抑郁的躯体化症状。这种情况在女性人群中更为常见。本临床研究旨在评估女性人群中由腰椎椎管狭窄引起的腰痛程度与抑郁之间的相关性。

方法

该研究纳入了 50 例连续的女性椎管狭窄患者。狭窄的诊断是通过神经系统检查和神经影像学做出的。研究组进行了精神病学评估,并分为有抑郁和无抑郁两组。使用视觉模拟量表(VAS)、Oswestry 残疾指数(ODI)和汉密尔顿抑郁量表(HDS)对组进行初始评估。

结果

21 例腰椎椎管狭窄患者患有抑郁(DLS 组),29 例无抑郁(LSS 组)。LSS 组和 DLS 组的 HDS 评分均值分别为 8.97 和 32.48。两组 VAS 评分存在统计学差异(LSS 组和 DLS 组的平均 VAS 评分分别为 5.6 和 7.6)。LSS 组(65.24±4.58)和 DLS 组(75.1±6.7)的平均 ODI 值也存在显著差异。在 DLS 组中,ODI 与 VAS 与 HDS 之间存在正相关(p<0.001)。

结论

我们的研究结果表明,腰椎椎管狭窄相关疼痛程度与抑郁之间存在相关性。然而,因果关系仍需进一步确定。

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