Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Istanbul University, Cerrahpasa School of Medicine, Istanbul, Turkey.
J Assist Reprod Genet. 2012 Jul;29(7):589-95. doi: 10.1007/s10815-012-9754-6. Epub 2012 Apr 11.
To investigate whether serum anti-müllerian hormone (AMH), follicle stimulating hormone (FSH), or antral follicle count (AFC) are predictive for clinical pregnancy in in vitro fertilization (IVF) patients.
Serum AMH, inhibin B, FSH, luteinizing hormone (LH), estradiol (E2), prolactin, and thyroid stimulating hormone (TSH) levels and AFC of 189 women under 40 years of age were investigated. Pregnant and non-pregnant women were compared.
Forty-seven (24.8 %) clinical pregnancies were observed in 189 women. There was no significant difference in terms of mean age, duration of infertility, body mass index, AMH, LH, FSH, E2, TSH, Inhibin B, AFC and total oocyte number between women who did and who did not become pregnant. Additionally, there was no significant difference in clinical pregnancy rates between the quartiles of AMH, FSH and AFC. (P values were 0.668, 0.071, and 0.252, respectively.)
Serum AMH and FSH, and AFC cannot predict clinical pregnancy in IVF patients under 40; the pregnancy rate tends to increase as AMH increases, although this remains non-significant.
研究血清抗缪勒管激素（AMH）、卵泡刺激素（FSH）或窦卵泡计数（AFC）是否可预测体外受精（IVF）患者的临床妊娠。
对 189 名年龄小于 40 岁的女性的血清 AMH、抑制素 B、FSH、黄体生成素（LH）、雌二醇（E2）、催乳素、促甲状腺激素（TSH）水平和 AFC 进行了研究。比较了妊娠和非妊娠女性。
在 189 名女性中观察到 47 例（24.8%）临床妊娠。妊娠组和未妊娠组之间的平均年龄、不孕持续时间、体重指数、AMH、LH、FSH、E2、TSH、抑制素 B、AFC 和总卵母细胞数均无显著差异。此外，AMH、FSH 和 AFC 的四分位数之间的临床妊娠率无显著差异（P 值分别为 0.668、0.071 和 0.252）。
血清 AMH 和 FSH 以及 AFC 不能预测 40 岁以下 IVF 患者的临床妊娠；虽然这仍然没有统计学意义，但随着 AMH 的增加，妊娠率有上升的趋势。
