Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey.
Angiology. 2013 Apr;64(3):200-4. doi: 10.1177/0003319712440619. Epub 2012 Apr 9.
We investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of high levels of SYNTAX score (SXscore) in patients with acute myocardial infarction. Patients (n = 281; male 77%; mean age 60 ± 12) who were admitted with ST-elevation myocardial infarctions (STEMIs) were enrolled. Patients were divided into 2 groups. Group 1 was defined as SXscore <22 and group 2 was defined as SXscore ≥22. Total bilirubin levels were significantly higher in the high-SXscore group than in the low-SXscore group (0.86 ± 0.42 vs 1.02 ± 0.51, P = .005). A significant correlation was detected between total bilirubin and SXscore (r = .42; P = .001). At multivariate analysis, total bilirubin (odds ratio: 1.86, 95% confidence interval 1.04-3.35; P = .038) was an independent risk factor for high SXscore in patients with STEMI. In conclusion, serum bilirubin level is independently associated with SXscore in patients with STEMI.
我们研究了血清胆红素水平（血红素加氧酶活性的标志物）是否可预测急性心肌梗死患者中 SYNTAX 评分（SXscore）较高的水平。纳入了因 ST 段抬高型心肌梗死（STEMI）而入院的 281 例患者（男性占 77%；平均年龄 60 ± 12 岁）。患者被分为两组。组 1 的定义为 SXscore <22，组 2 的定义为 SXscore ≥22。高 SXscore 组的总胆红素水平明显高于低 SXscore 组（0.86 ± 0.42 对 1.02 ± 0.51，P =.005）。总胆红素与 SXscore 之间存在显著相关性（r =.42；P =.001）。多元分析显示，总胆红素（比值比：1.86，95%置信区间 1.04-3.35；P =.038）是 STEMI 患者高 SXscore 的独立危险因素。总之，血清胆红素水平与 STEMI 患者的 SXscore 独立相关。
