Rknots：用 R 进行的生物聚合物的纽结拓扑分析。

Rknots: topological analysis of knotted biopolymers with R.

机构信息

Department of Biosystems Science and Engineering, ETH Zurich, Basel, CH-4058, Switzerland.

出版信息

Bioinformatics. 2012 May 15;28(10):1400-1. doi: 10.1093/bioinformatics/bts160. Epub 2012 Apr 5.

Abstract

Rknots is a flexible R package providing tools for the detection and characterization of topological knots in biological polymers. The package is well documented and provides a simple syntax for data import and preprocessing, structure reduction, topological analyses and 2D and 3D visualization. Remarkably, Rknots is not limited to protein knots and allows researchers from interdisciplinary fields to analyze different topological structures and to develop simple yet fully custom pipelines.

摘要

Rknots 是一个灵活的 R 包，提供了用于检测和描述生物聚合物中拓扑结的工具。该包有详细的文档，并提供了简单的语法，用于数据导入和预处理、结构约简、拓扑分析以及 2D 和 3D 可视化。值得注意的是，Rknots 不仅限于蛋白质结，它允许跨学科领域的研究人员分析不同的拓扑结构，并开发简单但完全定制的流程。