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预防中风的颈动脉支架:一种非手术选择。

Carotid stents to prevent stroke: a nonsurgical option.

作者信息

White Christopher J, Ramee Stephen R, Collins Tyrone J, Jenkins J Stephen, Silva Jose A, Chan Albert W, Reily J P, Qunitana Hugo A, Felberg Robert A, McKinley Kevin L

出版信息

Ochsner J. 2003 Winter;5(1):18-23.

Abstract

Angioplasty and stent placement have become accepted alternatives to surgery in many vascular territories. The most recent application of percutaneous intervention has been to explore its clinical utility and safety for stroke prevention in carotid arteries. Over the past 8 years, from January 1994 until Nov 2002, we performed 449 elective carotid stent procedures in 426 patients and in 481 vessels. Informed consent was obtained from each patient. Success was achieved in 97.3% of the patients treated. After one month of follow-up, 12 (2.8%) patients experienced stroke or death. After an average of 2.8 ± 1.7 years (range 1 month to 8.8 years) of follow-up, restenosis was found in 11 (2.6%) patients and was treated with balloon angioplasty. Our results, in a predominantly high-risk surgery group of patients, suggest that carotid stent placement is a viable treatment alternative to conventional surgery. It is likely that as the technology continues to evolve, the procedural risks of stroke and death will be minimized by embolic protection devices, making carotid stenting an option for low-risk surgical patients.

摘要

血管成形术和支架置入术已成为许多血管区域手术的可接受替代方案。经皮介入的最新应用是探索其在预防颈动脉卒中方面的临床效用和安全性。在1994年1月至2002年11月的过去8年中,我们对426例患者的481条血管进行了449例择期颈动脉支架置入手术。每位患者均获得了知情同意。接受治疗的患者中有97.3%取得了成功。随访1个月后,12例(2.8%)患者发生卒中或死亡。平均随访2.8±1.7年(范围1个月至8.8年)后,11例(2.6%)患者出现再狭窄,并接受了球囊血管成形术治疗。我们在主要为高风险手术患者群体中的结果表明,颈动脉支架置入术是传统手术的一种可行替代治疗方法。随着技术的不断发展,栓塞保护装置可能会将卒中及死亡的手术风险降至最低,使颈动脉支架置入术成为低风险手术患者的一种选择。

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