Guldfred L-A, Philipsen B B, Siim C
Department of Otolaryngology, Roskilde County Hospital, Denmark.
J Laryngol Otol. 2012 Jun;126(6):598-604. doi: 10.1017/S0022215112000473. Epub 2012 Apr 12.
To examine the accuracy of the pre-operative diagnosis of branchial cleft anomalies, and also to describe their occurrence, clinical presentation and management.
Retrospective review of the records of patients diagnosed with a branchial cleft anomaly between 1997 and 2006.
One hundred and twenty-six patients were included. Pre-operative diagnosis had a positive predictive value of 0.856 (95 per cent confidence interval, 0.771-0.918) and a sensitivity of 0.944 (95 per cent confidence interval, 0.869-0.979). These patients' demographic data, investigations, findings and management are presented, along with a possible strategy for dealing with solitary cystic masses in the neck.
As pre-operative diagnosis has a positive predictive value of 86 per cent, cystic lesions in the neck should be presumed to be carcinomatous until proven otherwise. Branchial fistulae and sinuses seem to be a disease of childhood, while branchial cysts occur mainly in adults. Branchial cleft anomalies are equally frequent in men and women, and equally distributed on the left and right side of the neck.
探讨鳃裂畸形术前诊断的准确性,并描述其发生率、临床表现及治疗方法。
回顾性分析1997年至2006年间诊断为鳃裂畸形患者的病历资料。
共纳入126例患者。术前诊断的阳性预测值为0.856(95%置信区间为0.771 - 0.918),敏感性为0.944(95%置信区间为0.869 - 0.979)。文中呈现了这些患者的人口统计学数据、检查、发现及治疗情况,以及处理颈部孤立性囊性肿物的可能策略。
由于术前诊断的阳性预测值为86%,颈部囊性病变在未证实并非癌性病变之前应被假定为癌性病变。鳃裂瘘管和窦道似乎是儿童期疾病,而鳃裂囊肿主要发生于成人。鳃裂畸形在男性和女性中发生率相同,在颈部左右两侧分布也相同。