Ascoli M
Biochim Biophys Acta. 1979 Sep 3;586(3):608-14. doi: 10.1016/0304-4165(79)90051-5.
The ability of leupeptin to block the degradation of receptor-bound human choriogonadotropin has been studied. It was found that this compound inhibited hormone degradation and intracellular cathepsin B activity in a parallel fasion, without affecting hormone-stimulated steroidogenesis.
已对亮抑蛋白酶肽阻断受体结合型人绒毛膜促性腺激素降解的能力进行了研究。发现该化合物以平行方式抑制激素降解和细胞内组织蛋白酶B活性,而不影响激素刺激的类固醇生成。