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畜舍犬中兽疫链球菌亚种和强力霉素耐药性的遗传多样性。

Genetic diversity of Streptococcus equi subsp. zooepidemicus and doxycycline resistance in kennelled dogs.

机构信息

The Royal Veterinary College, Department of Pathology and Infectious Diseases, Hatfield, United Kingdom.

出版信息

J Clin Microbiol. 2012 Jun;50(6):2134-6. doi: 10.1128/JCM.00719-12. Epub 2012 Apr 11.

Abstract

The genetic diversity and antibiotic resistance profiles of 38 Streptococcus equi subsp. zooepidemicus isolates were determined from a kennelled canine population during two outbreaks of hemorrhagic pneumonia (1999 to 2002 and 2007 to 2010). Analysis of the szp gene hypervariable region and the 16S-23S rRNA intergenic spacer region and multilocus sequence typing (MLST) indicated a predominant tetO-positive, doxycycline-resistant ST-10 strain during 1999 to 2002 and a predominant tetM-positive doxycycline-resistant ST-62 strain during 2007 to 2010.

摘要

从两次出血性肺炎爆发(1999 年至 2002 年和 2007 年至 2010 年)期间的犬舍犬群中,确定了 38 株马链球菌兽疫亚种的遗传多样性和抗生素耐药谱。对 szp 基因高变区和 16S-23S rRNA 基因间隔区以及多位点序列分型(MLST)的分析表明,1999 年至 2002 年期间主要为 tetO 阳性、强力霉素耐药的 ST-10 株,而 2007 年至 2010 年期间主要为 tetM 阳性、强力霉素耐药的 ST-62 株。

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