Holzbach T, Artunian N, Spanholtz T A, Volkmer E, Engelhardt T O, Giunta R E
Handchirurgie, Plastische Chirurgie, Ästhetische Chirurgie, Ludwig-Maximilians-Universität München, München. T
Handchir Mikrochir Plast Chir. 2012 Apr;44(2):84-8. doi: 10.1055/s-0032-1309023. Epub 2012 Apr 11.
The knowledge of tissue perfusion has not only a prognostic value in microvascular surgery but also the intraoperative detection of malperfusion can lead to a quick surgical intervention. Indocyanine green (ICG) angiography allows a topographic analysis of perfusion and is used to assess lymphatic drainage pathways and to analyse the depth of burn injuries. Integrating the technique into an operating microscope enables visualisation of the flow over microanastomoses and allows the assessment of the transit time of blood flow between arterial and venous anastomosis. Using this method we analysed 11 microsurgical free flaps (3 latissimus dorsi, 3 rectus abdominis, 1 gracilis muscle, 2 radial forearm, 1 ALT, and 1 DIEP flap). The topographic analysis was performed after the assessment of the microanastomoses. We observed no flap loss or partial flap necrosis. The transit time between arterial inflow and venous outflow was 32.8 s on average. Here we observed distinct differences between muscle flaps (27.7 s) on the one hand and fasciocutaneous and perforator flaps (47.5 s) on the other hand. We detected one venous thrombosis by ICG angiography in a case where the clinical patency test was not distinct. Revision was performed immediately. Particularly for intraoperative assessment, ICG angiography is a useful, reliable and safe technique. The integration into the operating microscope allows an "angiographic patency test" and the analysis of the transit time allows the evaluation of blood flow within the flap. Especially when planning perforator flaps the method of ICG angiography provides a new level of safety in flap design by quickly demonstrating the borders of perfusion.
组织灌注知识不仅在微血管手术中具有预后价值,而且术中检测到灌注不良可促使迅速进行手术干预。吲哚菁绿(ICG)血管造影可对灌注进行局部分析,用于评估淋巴引流途径和分析烧伤深度。将该技术集成到手术显微镜中,能够可视化微血管吻合处的血流,并评估动脉和静脉吻合之间的血流通过时间。我们使用这种方法分析了11个游离显微皮瓣(3个背阔肌皮瓣、3个腹直肌皮瓣、1个股薄肌皮瓣、2个桡侧前臂皮瓣、1个股前外侧皮瓣和1个腹壁下动脉穿支皮瓣)。在评估微血管吻合后进行局部分析。我们未观察到皮瓣丢失或部分皮瓣坏死。动脉流入和静脉流出之间的通过时间平均为32.8秒。在此,我们观察到一方面肌肉皮瓣(27.7秒)与另一方面筋膜皮瓣和穿支皮瓣(47.5秒)之间存在明显差异。在一例临床通畅试验不明确的病例中,我们通过ICG血管造影检测到1例静脉血栓形成,并立即进行了翻修。特别是对于术中评估,ICG血管造影是一种有用、可靠且安全的技术。集成到手术显微镜中可进行“血管造影通畅试验”,而通过时间分析可评估皮瓣内的血流情况。尤其是在设计穿支皮瓣时,ICG血管造影方法通过快速显示灌注边界,为皮瓣设计提供了新的安全水平。