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[支气管动脉灌注化疗联合或不联合放疗治疗晚期肺癌]

[Bronchial arterial infusion chemotherapy with or without radiotherapy for advanced lung cancer].

作者信息

Huang D P

机构信息

Hankou Air Force Hospital, PLA, Wuhan.

出版信息

Zhonghua Zhong Liu Za Zhi. 1990 May;12(3):216-8.

PMID:2249598
Abstract

Forty-two patients with Stage III and IV advanced lung cancer received bronchial arterial infusion of Cyclophosphamide or Mitomycin in combination with Adriamycin and Cisplatin (CAP or MAP). Twenty-six patients were given radiotherapy too. Histologically, 16 had squamous cell carcinoma, 11 adenocarcinoma, 3 small cell anaplastic carcinoma and 1 un-classified cancer. Eleven were diagnosed by bronchial arterial radiography. The short-term results showed that complete response rate (CR) was 53.8% and partial response rate (PR) 38.5% in patients treated with combined chemotherapy and radiotherapy whereas in those treated with infusion chemotherapy, CR and PR were 0% and 81.3% respectively.

摘要

42例Ⅲ期和Ⅳ期晚期肺癌患者接受了支气管动脉灌注环磷酰胺或丝裂霉素,联合阿霉素和顺铂(CAP或MAP方案)治疗。26例患者还接受了放射治疗。组织学检查显示,16例为鳞状细胞癌,11例为腺癌,3例为小细胞未分化癌,1例为未分类癌。11例通过支气管动脉造影确诊。短期结果显示,联合化疗和放疗的患者完全缓解率(CR)为53.8%,部分缓解率(PR)为38.5%;而接受灌注化疗的患者,CR和PR分别为0%和81.3%。

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