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肺癌支气管动脉化疗灌注的结果——82例报告

[Results of bronchial artery chemotherapy infusion in lung cancer--report of 82 cases].

作者信息

Pang Q Q

机构信息

Nanjing Chest Hospital.

出版信息

Zhonghua Zhong Liu Za Zhi. 1989 Jan;11(1):60-3.

PMID:2550201
Abstract

Eighty-two patients with lung cancer confirmed by cytology and/or histology were treated by bronchial artery chemotherapy infusion. There were 61 males and 21 females. The ages ranged from 30 to 75 years with an average of 54.6. Histologic types were 48 squamous cell carcinomas (58.5%), 20 adenocarcinomas (24.4%), and 14 undifferentiated small cell carcinomas (17.1%). TNM classification showed 28 Stage IIIa, 32 Stage IIIb and 22 Stage IV. Sixty-nine patients were treated by Cis-platinum combined with cyclophosphamide (84.1%). The results showed that 20 patients had complete response (24.4%), 28 partial response (34.1%), 25 stability (30.5%), 8 progression (9.8%) and 1 died (1.2%). Ten patients underwent lung resection after infusion of drugs. The factors influencing prognosis and complications are discussed.

摘要

82例经细胞学和/或组织学确诊的肺癌患者接受了支气管动脉化疗灌注治疗。其中男性61例,女性21例。年龄范围为30至75岁,平均年龄54.6岁。组织学类型为48例鳞状细胞癌(58.5%)、20例腺癌(24.4%)和14例未分化小细胞癌(17.1%)。TNM分期显示28例Ⅲa期、32例Ⅲb期和22例Ⅳ期。69例患者接受顺铂联合环磷酰胺治疗(84.1%)。结果显示,20例患者完全缓解(24.4%),28例部分缓解(34.1%),25例病情稳定(30.5%),8例进展(9.8%),1例死亡(1.2%)。10例患者在药物灌注后接受了肺切除术。文中讨论了影响预后和并发症的因素。

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