Wasoontarajaroen Siriwat, Thansandote Artnarong, Gajda Gregory B, Lemay Eric P, McNamee James P, Bellier Pascale V
Faculty of Engineering, Rajamangala University of Technology Isan Khonkaen Campus, Khon Kaen, Thailand.
Bioelectromagnetics. 2012 Oct;33(7):575-84. doi: 10.1002/bem.21714. Epub 2012 Apr 11.
An exposure system, consisting of four identical cylindrical waveguide chambers, was developed for studying the effects of radiofrequency (RF) energy on laboratory mice at a frequency of 1.9 GHz. The chamber was characterized for RF dose rate as a function of animal body mass and dose rate variations due to animal movement in the cage. Dose rates were quantified in terms of whole-body average (WBA) specific absorption rate (SAR), brain average (BA) SAR and peak spatial-average (PSA) SAR using measurement and computational methods. Measurements were conducted on mouse cadavers in a multitude of possible postures and positions to evaluate the variations of WBA-SAR and its upper and lower bounds, while computations utilizing the finite-difference time-domain method together with a heterogeneous mouse model were performed to determine variations in BA-SAR and the ratio of PSA-SAR to WBA-SAR. Measured WBA-SAR variations were found to be within the ranges of 9-23.5 W/kg and 5.2-13.8 W/kg per 1 W incident power for 20 and 40 g mice, respectively. Computed BA-SAR variations were within the ranges of 3.2-10.1 W/kg and 3.3-9.2 W/kg per 1 W incident power for 25 and 30 g mouse models, respectively. Ratios of PSA-SAR to WBA-SAR, averaged over 0.5 mg and 5 mg tissue volumes, were observed to be within the ranges of 6-15 and 4-10, respectively.
开发了一种由四个相同的圆柱形波导腔组成的暴露系统，用于研究射频（RF）能量在1.9 GHz频率下对实验室小鼠的影响。该腔室的特征在于射频剂量率与动物体重的函数关系，以及由于动物在笼中的移动导致的剂量率变化。使用测量和计算方法，根据全身平均（WBA）比吸收率（SAR）、脑平均（BA）SAR和峰值空间平均（PSA）SAR对剂量率进行了量化。在多种可能的姿势和位置下对小鼠尸体进行测量，以评估WBA-SAR的变化及其上下限，同时利用有限时域差分法结合异质小鼠模型进行计算，以确定BA-SAR的变化以及PSA-SAR与WBA-SAR的比值。对于20克和40克的小鼠，每1瓦入射功率下测量的WBA-SAR变化分别在9-23.5 W/kg和5.2-13.8 W/kg范围内。对于25克和30克的小鼠模型，每1瓦入射功率下计算的BA-SAR变化分别在3.2-10.1 W/kg和3.3-9.2 W/kg范围内。在0.5毫克和5毫克组织体积上平均的PSA-SAR与WBA-SAR的比值分别在6-15和4-10范围内。
