Kelsey Thomas W, Wallace W Hamish B
School of Computer Science, University of St. Andrews, St. Andrews, Scotland, Kelsey KY16 9SX, UK.
Obstet Gynecol Int. 2012;2012:305025. doi: 10.1155/2012/305025. Epub 2012 Feb 12.
A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r = 0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r = 0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm(3) volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman.
对个体女性的卵巢储备进行可靠的间接测量，仍然是生殖专家面临的一项挑战。通过对一项关于卵巢体积的大规模研究的描述性统计，我们为25至85岁的健康女性建立了一个规范模型。就平均值而言，该模型与我们最近建立的25至51岁女性卵巢中静止卵泡（NGF）模型具有很强的正相关性（r = 0.89）。当对两个模型进行对数调整后，在整个卵巢体积范围内，相关性增加到r = 0.99。此外，我们可以推断，体积为3立方厘米（或更小）的卵巢大约包含1000个静止卵泡（或更少）。这些强相关性表明，卵巢体积是间接估计个体女性人类卵巢储备的一个有用因素。
