Ther Adv Urol. 2012 Apr;4(2):77-83. doi: 10.1177/1756287212437361.
One of the challenges facing primary care physicians and specialists as the population ages is the management of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). While as many as 18% of men in their 40s report bother from an enlarged prostate, that figure rises dramatically, whereby 50% of men in their 50s and 90% of men in their 90s will complain of bothersome symptoms related to an enlarged prostate. Studies have shown that BPH is a progressive disease, which if left untreated can result in worsening of symptoms, acute urinary retention and renal failure. Until about 20 years ago the only management option available to urologists was surgery. In the early 1990s medical therapy emerged as the predominant treatment for BPH. Therapy may be tailored to target symptoms and progression of disease.
随着人口老龄化，初级保健医生和专家面临的挑战之一是管理良性前列腺增生（BPH）引起的下尿路症状（LUTS）。虽然多达 18%的 40 多岁男性报告因前列腺增大而感到不适，但这一数字急剧上升，50%的 50 多岁男性和 90%的 90 多岁男性会抱怨与前列腺增大相关的恼人症状。研究表明，BPH 是一种进行性疾病，如果不治疗，可能会导致症状恶化、急性尿潴留和肾衰竭。直到大约 20 年前，泌尿科医生唯一可用的治疗选择是手术。20 世纪 90 年代初，药物治疗成为 BPH 的主要治疗方法。治疗方法可以根据症状和疾病进展进行调整。
