原生动物感染中的巨噬细胞移动抑制因子
Macrophage migration inhibitory factor in protozoan infections.
作者信息
Bozza Marcelo T, Martins Yuri C, Carneiro Letícia A M, Paiva Claudia N
机构信息
Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
出版信息
J Parasitol Res. 2012;2012:413052. doi: 10.1155/2012/413052. Epub 2012 Feb 9.
Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.
巨噬细胞移动抑制因子（MIF）是一种在免疫和炎症反应中起核心作用的细胞因子。在本文中，我们讨论了MIF在原生动物寄生虫感染免疫反应中的参与情况。一般而言，MIF以因炎症增加导致组织损伤为代价参与控制寄生虫负荷。
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