Lohmann W, Schreiber J, Gerhardt H, Breithaupt H, Löffler H, Pralle H
Blut. 1979 Aug;39(2):147-51. doi: 10.1007/BF01008090.
ESR investigations of lyophilized blood of patients with acute lymphatic leukemia exhibit an increase in spin concentration and an additional peak not present in control samples. This peak disappears almost completely concomittantly with a reduction in spin concentration after treating the patients with prednisolone, vincristine, and doxorubicin or after addition of 5mM of CuCl2 to blood samples. The results show that the ESR spectra of lyophilized blood samples can be utilized to follow the effect of therapy. Moreover, they suggest that the leukemic blood possesses a high concentration of antioxidants.
对急性淋巴细胞白血病患者冻干血液进行的电子自旋共振(ESR)研究显示,自旋浓度增加,且出现了对照样本中不存在的额外峰。在用泼尼松龙、长春新碱和阿霉素治疗患者后,或在血液样本中加入5mM氯化铜后,该峰几乎完全消失,同时自旋浓度降低。结果表明,冻干血液样本的ESR光谱可用于跟踪治疗效果。此外,这些结果表明白血病血液中抗氧化剂浓度较高。