Parasitology Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Henri-Dunant Rd., Bangkok 10330, Thailand.
Vet Parasitol. 2012 Aug 13;188(1-2):25-30. doi: 10.1016/j.vetpar.2012.02.021. Epub 2012 Mar 10.
The seroprevalence of Toxoplasma gondii, Dirofilaria immitis (heartworm), feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infections was examined using serum or plasma samples from 746 pet cats collected between May and July 2009 from clinics and hospitals located in and around Bangkok, Thailand. The samples were tested for heartworm, FIV, and FeLV using a commercial ELISA. Of the 746 samples, 4.6% (34/746) were positive for heartworm antigen, 24.5% (183/746) had circulating FeLV antigen, and 20.1% (150/746) had antibodies against FIV. In addition, the first 348 submitted samples were tested for T. gondii antibodies using a modified agglutination test (MAT, cut off 1:25); 10.1% (35/348) were seropositive. Of the 348 cats sampled for all four pathogens, 11, 10, and 1 were positive for T. gondii antibodies and FIV antibodies, FeLV antigen, or D. immitis antigen, respectively. Of the 35 T. gondii-seropositive cats, 42.9% (15/35) were co-infected with at least one of the other three pathogens. The presence of antibodies to FIV was significantly associated with both age and gender, while FeLV antigen presence was only associated with age. In the case of FIV, males were twice as likely to be infected as females, and cats over 10 years of age were 13.5 times more likely to be infected than cats less than 1 year of age. FeLV antigen was more common in younger cats, with cats over 10 years of age being 10 times less likely to be FeLV positive than cats under 1 year of age. This is the first survey for these four pathogens affecting feline health in Thailand.
2009 年 5 月至 7 月期间，从泰国曼谷及周边地区的诊所和医院采集了 746 只宠物猫的血清或血浆样本，检测了这些样本中弓形虫、犬恶丝虫（心丝虫）、猫免疫缺陷病毒（FIV）和猫白血病病毒（FeLV）的感染情况。采用商业 ELISA 法检测了心丝虫、FIV 和 FeLV。在 746 个样本中，有 4.6%（34/746）为心丝虫抗原阳性，24.5%（183/746）有循环 FeLV 抗原，20.1%（150/746）有针对 FIV 的抗体。此外，对前 348 个提交样本进行了改良凝集试验（MAT，截值 1:25）以检测 T. gondii 抗体；有 10.1%（35/348）呈阳性。在对所有四种病原体进行采样的 348 只猫中，分别有 1、10 和 1 只猫的 T. gondii 抗体和 FIV 抗体、FeLV 抗原或 D. immitis 抗原检测结果呈阳性。在 35 只 T. gondii 抗体阳性的猫中，有 42.9%（15/35）同时感染了其他三种病原体中的至少一种。FIV 抗体的存在与年龄和性别显著相关，而 FeLV 抗原的存在仅与年龄相关。在 FIV 方面，雄性感染的可能性是雌性的两倍，10 岁以上的猫感染的可能性是 1 岁以下猫的 13.5 倍。FeLV 抗原在幼猫中更为常见，10 岁以上的猫 FeLV 阳性的可能性比 1 岁以下的猫低 10 倍。这是首次在泰国对影响猫健康的这四种病原体进行的调查。
