Walter and Eliza Hall Institute, 1G Royal Melbourne Hospital, Parkville 3052, Australia.
Curr Biol. 2012 Apr 10;22(7):R235-7. doi: 10.1016/j.cub.2012.02.045.
Three recent papers provide striking insight into the mechanisms used to regulate B-cell differentiation. They demonstrate that B-cell fate choice can be stochastic, directed, inherited, or some combination of these, depending on the circumstances. The trick is going to be working out which is important when.
三篇最近的论文深入探讨了调控 B 细胞分化的机制，令人瞩目。它们表明，B 细胞命运的选择可以是随机的、定向的、遗传的，或者这些因素的某种组合，具体取决于环境。关键在于弄清楚在什么情况下哪种因素是重要的。
