B 细胞分化：有指导的一天，随机的下一天。
B-cell differentiation: instructive one day, stochastic the next.
机构信息
Walter and Eliza Hall Institute, 1G Royal Melbourne Hospital, Parkville 3052, Australia.
出版信息
Curr Biol. 2012 Apr 10;22(7):R235-7. doi: 10.1016/j.cub.2012.02.045.
PMID:22497941
Abstract
Three recent papers provide striking insight into the mechanisms used to regulate B-cell differentiation. They demonstrate that B-cell fate choice can be stochastic, directed, inherited, or some combination of these, depending on the circumstances. The trick is going to be working out which is important when.
摘要
三篇最近的论文深入探讨了调控 B 细胞分化的机制，令人瞩目。它们表明，B 细胞命运的选择可以是随机的、定向的、遗传的，或者这些因素的某种组合，具体取决于环境。关键在于弄清楚在什么情况下哪种因素是重要的。
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