Department of Communication Disorders, University of Canterbury, Van der Veer Institute for Parkinson's and Brain Research, Christchurch, New Zealand.
Arch Phys Med Rehabil. 2012 Nov;93(11):2000-7. doi: 10.1016/j.apmr.2012.02.015. Epub 2012 Mar 5.
To investigate the immediate and late effects of submental event-related neuromuscular electrical stimulation (NMES) on pharyngeal pressure generation during noneffortful and effortful saliva swallows.
Before-after trial.
Swallowing rehabilitation research laboratory.
Sex-matched (N=20) healthy research volunteers.
Participants received 80Hz NMES of 4-second duration to floor of mouth muscles that was time-locked to 60 volitional saliva swallows.
Manometry measures of peak pressures and duration of pressure events in the oropharynx, hypopharynx, and the upper esophageal sphincter (UES) were derived during execution of noneffortful and effortful saliva swallows. Measures were taken at baseline, during stimulation, and at 5-, 30-, and 60-minutes poststimulation.
Baseline pharyngeal and UES pressures did not differ between stimulated and nonstimulated swallows. At 5- and 30-minutes poststimulation, peak pressure decreased at the hypopharyngeal and at the UES sensor during noneffortful swallows. The effect lasted up to an hour only in the hypopharynx. No changes in duration of pressure events were observed.
Using this treatment paradigm, decreased peak amplitude in the hypopharynx up to an hour after treatment indicates a potential risk of decreased bolus flow associated with NMES. On the other hand, decreased UES relaxation pressure may facilitate bolus transit into the esophagus.
研究颏下事件相关神经肌肉电刺激（NMES）对非用力和用力唾液吞咽时咽压产生的即时和迟发效应。
前后试验。
吞咽康复研究实验室。
性别匹配的（N=20）健康研究志愿者。
参与者接受 80Hz、4 秒时长的 NMES，刺激时间锁定在 60 次自主唾液吞咽时。
在执行非用力和用力唾液吞咽时，从测压法中得出口咽、下咽和上食管括约肌（UES）的峰值压力和压力事件持续时间。在基线、刺激期间以及刺激后 5、30 和 60 分钟进行测量。
在刺激和非刺激吞咽时，基础咽和 UES 压力没有差异。在刺激后 5 和 30 分钟，非用力吞咽时，下咽和 UES 传感器的峰值压力降低。这种效应仅在下咽持续了一个小时。压力事件持续时间没有变化。
使用这种治疗模式，治疗后一个小时内咽部下段的峰值幅度降低表明 NMES 可能会降低食团的流动速度。另一方面，UES 松弛压力的降低可能会促进食团进入食管。
