University College London Hospitals NHS Foundation Trust, London, UK.
Curr Opin Support Palliat Care. 2012 Jun;6(2):194-200. doi: 10.1097/SPC.0b013e328352edff.
To address the issues of the scale and diversity of chronic pain in neurological disorders and the evidence for effective treatment of pain in these conditions.
Contemporary literature supports the notion that pain in neurological conditions is common and has tended to be underestimated.
Pain in neurological disease displays great diversity in putative mechanisms and clinical presentation. Rational management requires an analysis of likely mechanisms of pain generation as a guide to treatment. Some common neurological disorders are briefly discussed, primarily to provide an indication of the range of pain phenotypes observed across the spectrum of neurological disease. Treatments are reviewed with an emphasis on systemic drugs and the current best evidence for their use.
解决神经障碍慢性疼痛的规模和多样性问题，以及这些情况下有效治疗疼痛的证据。
当代文献支持这样一种观点，即神经疾病中的疼痛很常见，而且往往被低估了。
神经疾病中的疼痛在潜在机制和临床表现上显示出极大的多样性。合理的管理需要对疼痛产生的可能机制进行分析，作为治疗的指导。一些常见的神经障碍疾病被简要讨论，主要是为了说明在神经疾病谱中观察到的疼痛表型的范围。治疗方法的综述侧重于系统药物以及目前对其使用的最佳证据。
