Boettcher F A, Salvi R J, Saunders S S
Department of Communicative Disorders and Sciences, SUNY-Buffalo 14214.
Hear Res. 1990 Sep;48(1-2):125-44. doi: 10.1016/0378-5955(90)90203-2.
Recovery from short-term adaptation was measured in single neurons in the cochlear nucleus using a forward masking stimulus paradigm. The response to a short-duration, low-level probe tone at a unit's characteristic frequency (CF) was measured before and after presentation of a masker tone at the unit's CF. The degree of adaptation was defined as the ratio of firing to the probe in the adapted and unadapted conditions. The level of the masker and time difference between the masker offset and probe onset ('DT') were varied. As DT increased, the response to the probe increased in most Primarylike, Primarylike-notch, and Chopper units. Recovery was approximately linear in log time for most of these units. However, approximately half the Pauser/Buildup and On units showed very different recovery patterns, ranging from no adaptation to very non-linear recovery patterns. The results suggest that little alteration in the recovery process occurs between the auditory nerve and Primarylike, Primarylike-notch, and Chopper units, but that significant changes in the recovery process occur in Pauser-Buildup and On units.
使用前掩蔽刺激范式，在耳蜗核的单个神经元中测量短期适应的恢复情况。在以单位特征频率（CF）呈现掩蔽音之前和之后，测量对短持续时间、低强度探测音在单位CF处的反应。适应程度定义为适应和未适应条件下对探测音的放电率之比。掩蔽音的强度以及掩蔽音结束与探测音开始之间的时间差（“DT”）是变化的。随着DT增加，大多数初级样、初级样缺口和斩波单元对探测音的反应增加。对于大多数这些单元，恢复在对数时间内近似呈线性。然而，大约一半的暂停/增强和开启单元表现出非常不同的恢复模式，从不适应到非常非线性的恢复模式。结果表明，在听神经与初级样、初级样缺口和斩波单元之间，恢复过程几乎没有变化，但在暂停-增强和开启单元中，恢复过程发生了显著变化。
