[二次回归-正交设计优化黄芩苷乙醇提取工艺]
[Quadratic regression-orthogonal design optimization ethanol extraction craft of baicalin].
作者信息
Shi Lei, Zhang Zhen-Wei
机构信息
The 155th Central Hospital of PLA, Kaifeng 475003, China.
出版信息
Zhong Yao Cai. 2011 Dec;34(12):1946-50.
OBJECTIVE
To optimize the extraction process of baicalin using the quadratic regression-orthogonal design.
METHODS
The influential factors were ethanol doses, ethanol concentration and extract time. Used the high level statistical method to design experiment parameter and forecast analysis results.
RESULTS
The optimization conditions of extraction was 64% ethanol, 115 min for extract time,volume of use 11. 6 times and it's extraction rate was 85.21%.
CONCLUSION
It shows that the optimum model is simple,highly precision and highly predictive.
目的
采用二次回归正交设计优化黄芩苷的提取工艺。
方法
考察乙醇用量、乙醇浓度和提取时间等影响因素，运用高级统计学方法设计实验参数并预测分析结果。
结果
提取工艺的优化条件为乙醇浓度64%、提取时间115分钟、用量为11.6倍，提取率为85.21%。
结论
结果表明该优化模型简单、精度高、预测性强。
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