不同大孔树脂对黄芩苷吸附纯化工艺的研究
[Study on the technics of adsorption and purification of baicalin by different macroporous resins].
作者信息
Li Xiao-Min, Wu Xuan, Xiong Zhong-Liang, Ma Jin-Hua, Zhu Zhou-Fu
机构信息
College of animal science and technology, Southwest university, Chongqing 400715, China.
出版信息
Zhong Yao Cai. 2009 Oct;32(10):1613-5.
OBJECTIVE
To ascertain the fittest technical parameters by studying the application of macroporous resins used to purify active components of baicalin.
METHODS
To evaluate the ability of adsorption and re-adsorption of macroporous resins selected, the statical and dynamic adsorption-readsorption durations were also investigated to select the optimum macroporous resins, with the content of flavonoids as the standard.
RESULTS
The optimum macroporous resins was HPD-100. In the adsorption cours, the ratio between the amount of medicinal materials and the volume of macroporous resins was 3.0 and there was no more absorbed when the ratio was 12.5; the optimum ethanol concentration was 50% in readsorption duration.
CONCLUSION
HPD-100 is the optimum macroporous resin to purify bailcalin and enhance its refined rate.
目的
通过研究大孔树脂在黄芩苷活性成分纯化中的应用，确定最适宜的工艺参数。
方法
以黄酮类化合物含量为指标，考察所筛选大孔树脂的吸附及解吸附能力，研究静态和动态吸附 - 解吸附时间，以筛选最佳大孔树脂。
结果
最佳大孔树脂为HPD - 100。在吸附过程中，药材量与大孔树脂体积比为3.0，当比例为12.5时不再吸附；解吸附时最佳乙醇浓度为50%。
结论
HPD - 100是纯化黄芩苷、提高其精制率的最佳大孔树脂。
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