Department of Surgery, Section of Surgical Sciences, Vanderbilt University Medical Center, 1211 21st Avenue South, Nashville, TN 37232-0252, USA.
Gastroenterol Clin North Am. 2012 Jun;41(2):379-91. doi: 10.1016/j.gtc.2012.01.009. Epub 2012 Feb 24.
Perianal fistulizing disease is a common complication of CD that requires a multidisciplinary collaboration between gastroenterology, surgery, and radiology professionals for successful assessment and treatment. Optimal success comes from a combined medical and surgical approach to treat the fistulizing disease (see Fig. 1). Unfortunately, even with a variety of surgical options, a subset of patients require permanent fecal diversion and/or proctectomy to successfully treat their disease. Further studies (likely requiring large, multicenter trials) of novel medical and surgical treatments are still warranted to formulate optimal management of this complex condition.
肛周瘘管病是 CD 的常见并发症,需要胃肠病学、外科学和放射学专业人员之间的多学科协作,才能成功进行评估和治疗。最佳疗效来自于联合内科和外科方法来治疗瘘管病(参见图 1)。不幸的是,即使有多种手术选择,仍有一部分患者需要永久性粪便转流和/或直肠切除术才能成功治疗其疾病。仍需要进一步的研究(可能需要大型多中心试验)来探索新的内科和外科治疗方法,以制定这种复杂疾病的最佳治疗方案。