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克罗恩病中的沙曼氏体:病例报告及文献复习。

Schaumann bodies in Crohn's disease: a case report and review of the literature.

机构信息

Department of Pathology, A.O. Spedali Civili di Brescia, Brescia, Italy.

出版信息

J Crohns Colitis. 2012 Aug;6(7):800-3. doi: 10.1016/j.crohns.2012.03.009. Epub 2012 Apr 12.

DOI:10.1016/j.crohns.2012.03.009
PMID:22503169
Abstract

Schaumann bodies are inclusion bodies, first described by Schaumann in 1941, typically seen in granulomatous diseases such as tuberculosis, sarcoidosis and chronic beryllium diseases. Williams WJ, in 1964, reported Schaumann bodies to occur in 10% of Crohn's disease (CD). We report a case of Crohn's disease, initially misdiagnosed as a schistosoma-related colitis for the presence of numerous calcified bodies resembling calcified ova and scattered granulomas. Subsequent biopsies showed more typical histological features and, in combination with a more complete clinical history, diagnosis of Crohn's disease was made.

摘要

绍曼氏体是包含体,于 1941 年由绍曼首次描述,通常见于肉芽肿性疾病,如结核、结节病和慢性铍病。威廉姆斯 WJ 于 1964 年报道,在 10%的克罗恩病(CD)中存在绍曼氏体。我们报告了一例克罗恩病,最初由于存在许多类似钙化卵的钙化体和散在的肉芽肿而误诊为与血吸虫有关的结肠炎。随后的活检显示出更典型的组织学特征,结合更完整的临床病史,作出了克罗恩病的诊断。

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1
Schaumann bodies in Crohn's disease: a case report and review of the literature.克罗恩病中的沙曼氏体:病例报告及文献复习。
J Crohns Colitis. 2012 Aug;6(7):800-3. doi: 10.1016/j.crohns.2012.03.009. Epub 2012 Apr 12.
2
Segmental colonoscopic biopsies in the differentiation of ileocolic tuberculosis from Crohn's disease.分段结肠镜活检在鉴别回结肠结核与克罗恩病中的应用
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Schaumann bodies deposited along myenteric plexus of the muscularis propria is a unique histopathological feature of Crohn's disease.沿固有肌层肌间神经丛沉积的舒曼小体是克罗恩病独特的组织病理学特征。
J Clin Pathol. 2025 Jan 17;78(2):96-102. doi: 10.1136/jcp-2023-209271.
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Colonic perforation in Crohn's disease.克罗恩病中的结肠穿孔
Gastroenterology. 1976 Nov;71(5):385-8.
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Problems in the differentiation of ulcerative colitis and Crohn's disease of the colon: the need for repeated diagnostic evaluation.结肠溃疡性结肠炎和克罗恩病鉴别诊断中的问题:重复诊断评估的必要性。
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Gastrointestinal: Colonic pulse granuloma complicating Crohn's disease.胃肠道:结肠脉冲性肉芽肿并发克罗恩病。
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[Granulomatous colitis associated with diverticular disease. Report of a case].[与憩室病相关的肉芽肿性结肠炎。病例报告]
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[A case of Crohn's disease associated with an intramural sinus tract of the transverse colon demonstrated pathohistology].[1例克罗恩病合并横结肠壁内窦道的病理组织学表现]
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引用本文的文献

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The First Case of Schaumann Bodies in Pediatric Very Early Onset Crohn's Disease: Case Report and Literature Review.小儿极早发型克罗恩病中首次出现绍曼小体病例:病例报告及文献综述
Children (Basel). 2024 Oct 6;11(10):1216. doi: 10.3390/children11101216.
2
Is the identification of caseating granuloma in the intestine indicative of tuberculosis? a rare case of Crohn's disease.肠道内干酪样肉芽肿的鉴定是否表明患有结核病?一例罕见的克罗恩病。
Diagn Pathol. 2024 Oct 22;19(1):139. doi: 10.1186/s13000-024-01566-2.
3
Granulomas in the gastrointestinal tract: deciphering the Pandora's box.
胃肠道中的肉芽肿:开启潘多拉魔盒之谜
Virchows Arch. 2018 Jan;472(1):3-14. doi: 10.1007/s00428-017-2210-3. Epub 2017 Aug 4.