Centre for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Reprod Biomed Online. 2012 Jun;24(6):634-8. doi: 10.1016/j.rbmo.2012.03.003. Epub 2012 Mar 14.
This is a retrospective, observational study to determine how often repeated consecutive miscarriages occur consistently in the same gestational period, including 1589 miscarriages among 543 women with recurrent miscarriage. In women who had two miscarriages only, 49.17% of both miscarriages occurred in the same gestational period, which was significantly higher than the expected probability of 34.54% (P<0.01). The proportions of all miscarriages occurring in the same gestational period in women with three, four and five or more miscarriages were 28.72%, 19.44% and 18.60%, compared with the expected probabilities of 14.36% (P<0.01), 6.57% (P<0.05) and <3.15% (P<0.05). The proportions of miscarriages occurring consistently in the same gestational period are higher than the theoretical probabilities calculated for the whole population.
这是一项回顾性观察研究,旨在确定反复性自然流产(RM)患者中连续发生的同一妊娠丢失(SCR)的频率,共纳入了 543 例 RM 患者的 1589 次流产。在仅发生过 2 次流产的患者中,有 49.17%的流产发生在同一妊娠时期,显著高于预期的 34.54%(P<0.01)。发生在同一妊娠时期的所有流产比例在发生过 3 次、4 次和 5 次或更多次流产的患者中分别为 28.72%、19.44%和 18.60%,而预期的概率分别为 14.36%(P<0.01)、6.57%(P<0.05)和 <3.15%(P<0.05)。发生在同一妊娠时期的流产比例高于针对全人群计算的理论概率。