Elguizaoui Sameh, Flanigan David C, Harris Joshua D, Parsons Erin, Litsky Alan S, Siston Robert A
The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Knee. 2012 Dec;19(6):812-7. doi: 10.1016/j.knee.2012.03.008. Epub 2012 Apr 12.
To determine whether proud synthetic and proud osteochondral plugs conform to native surrounding cartilage after cyclical loading and if there are differences in height and contact pressure after loading.
Sixteen bovine knees were used. Each received one osteochondral plug and one of two types of synthetic plugs (Smith & Nephew TruFit® BGS plug or Kensey Nash OsseoFit® plug). Plugs were placed in the center of each condyle's highest pressure area of articulation identified prior to defect creation (control). Static loads of 800N were applied and contact pressures measured with Tekscan sensors.
Both types of synthetic grafts and the osteochondral grafts all subsided with cyclical loading (p<0.001). The OsseoFit® plug displayed a greater reduction in height than the TruFit® plug compared to osteochondral grafts. The OsseoFit® plugs had significantly lower height than osteochondral grafts after both periods of cyclical loading (p<0.001), while height of the TruFit® plugs was not significantly different than the heights of osteochondral grafts after either first (p=0.387) or second (p=0.261) periods of cyclical loading. Contact pressures for the OsseoFit® plugs were significantly lower than contact pressures for osteochondral grafts after both periods of cyclical loading (p<0.001 for both). There was no difference between the pressures of TruFit® and osteochondral plugs after the first (p=0.381) or second (p=0.292) periods of cyclical loading.
Precision and accuracy are demanded to achieve flush osteochondral plug placement and OsseoFit synthetic plugs may subside more with less pressure than TruFit plugs if placed proud.
确定过高的合成材料填充块和过高的骨软骨移植块在周期性加载后是否与天然周围软骨贴合，以及加载后高度和接触压力是否存在差异。
使用16个牛膝关节。每个膝关节植入一个骨软骨移植块和两种类型的合成材料填充块中的一种（史赛克TruFit® BGS填充块或肯西·纳什OsseoFit®填充块）。在创建缺损之前，将填充块放置在每个髁的最高压力关节区域的中心（对照）。施加800N的静载荷，并用Tekscan传感器测量接触压力。
两种类型的合成材料移植块和骨软骨移植块在周期性加载后均出现下沉（p<0.001）。与骨软骨移植块相比，OsseoFit®填充块的高度降低幅度大于TruFit®填充块。在两个周期的周期性加载后，OsseoFit®填充块的高度均显著低于骨软骨移植块（p<0.001），而TruFit®填充块在第一个（p=0.387）或第二个（p=0.261）周期的周期性加载后的高度与骨软骨移植块的高度无显著差异。在两个周期的周期性加载后，OsseoFit®填充块的接触压力均显著低于骨软骨移植块的接触压力（两者均p<0.001）。在第一个（p=0.381）或第二个（p=0.292）周期的周期性加载后，TruFit®填充块和骨软骨移植块的压力无差异。
要实现骨软骨移植块的平齐放置，需要精确性和准确性，如果放置过高，OsseoFit合成材料填充块可能比TruFit填充块在压力较小的情况下下沉更多。
