Section of Psychiatry, Department of Neuroscience, University of Parma, Parma, Italy.
Psychiatry Res. 2012 Dec 30;200(2-3):422-9. doi: 10.1016/j.psychres.2012.03.016. Epub 2012 Apr 13.
Despite obvious clinical need, factors underlying early treatment discontinuation among 'real world' borderline personality disorder (BPD) patients are still unknown. This study investigates individual characteristics that can predict early (<three months) dropout among BPD outpatients at a general psychiatric service. Out of a sample of 1437 consecutively treatment-seeking psychiatric outpatients, 162 BPD subjects have been identified by means of the Structured Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) Personality. Sociodemographic, clinical and personality variables potentially relevant for dropout were assessed for all participants at baseline. Early dropouts (n=54) were compared to continuers (n=108) on all measures. Logistic regression was then used to identify independent predictors of early dropout. A history of suicide attempts predicted early discontinuation, whereas the presence of an eating disorder and of avoidant personality features protected from early dropout. If confirmed, these findings may help clinicians operating in general psychiatric settings with estimating the risk of premature treatment discontinuation, and stress the need to specifically address suicidal behaviours in order to improve treatment retention among borderline outpatients. In this regard, implementing general psychiatric care with specialised, evidence-based psychotherapeutic interventions may be deemed necessary.
尽管存在明显的临床需求,但“真实世界”边缘型人格障碍(BPD)患者早期治疗中断的根本原因仍不清楚。本研究旨在调查一般精神科服务中 BPD 门诊患者早期(<3 个月)脱落的个体特征。在一项连续治疗的 1437 名精神科门诊患者样本中,通过使用第四版精神障碍诊断和统计手册(DSM-IV)人格的结构化访谈,确定了 162 名 BPD 患者。所有参与者在基线时均评估了与脱落相关的社会人口统计学、临床和人格变量。将早期脱落者(n=54)与继续治疗者(n=108)进行比较。然后使用逻辑回归来确定早期脱落的独立预测因素。自杀未遂史预测了早期脱落,而饮食障碍和回避型人格特征则保护了患者不早期脱落。如果得到证实,这些发现可能有助于在一般精神科环境中工作的临床医生估计过早治疗中断的风险,并强调需要专门解决自杀行为,以提高边缘型门诊患者的治疗保留率。在这方面,实施具有专门、循证心理治疗干预的一般精神科护理可能被认为是必要的。