Tanaka Y
Dept. of Radiation Therapy, Tokyo Metropolitan Komagome Hospital.
Gan No Rinsho. 1990 Oct;36(13):2299-304.
For the treatment of brain tumors, radiation tolerance on the central nervous tissues is one of the most serious limiting factor, because glioblastoma has been considered as radioresistant. Radiation therapy in commonly employed dosages for malignant gliomas carries a risk of injury to surrounding cerebral tissues. Therefore, precision radiation therapy concerning that radiation field co-inside with the tumorous lesion is essentially important to intend obtaining an improvement of the local control rate without delayed radiation injuries. In this paper, a review of literatures as for radiation tolerance on the central nervous system and treatment policies with active intention for brain tumors are discussed.
对于脑肿瘤的治疗,中枢神经组织的辐射耐受性是最严重的限制因素之一,因为胶质母细胞瘤被认为具有放射抗性。常用于恶性胶质瘤的放射治疗剂量存在损伤周围脑组织的风险。因此,精确的放射治疗,即辐射野与肿瘤病变重合,对于在不造成延迟性放射损伤的情况下提高局部控制率至关重要。本文讨论了有关中枢神经系统辐射耐受性的文献综述以及针对脑肿瘤的积极治疗策略。